Each 100ml contains:
Bupivacaine Hydrochloride eq. to Anhydrous Bupivacaine Hydrochloride 5 mg
Dextrose (Monohydrate) 80 mg
Water for Injections q. s.


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Therapeutic indications:

Spinal anesthesia for surgery e.g. urological surgery and surgery on the lower limbs lasting 2-3 hours, abdominal surgery lasting 45- 60 minutes.

Special warnings and precautions for use:

One should be aware that spinal anesthesia can sometimes lead to major blocks, with paralysis of intercostal muscles and the diaphragm, especially in pregnant women.
Caution should be exercised in patients with degree II and III AV block since local anesthetics can lower the conduction capacity of myocardium. Elderly patients and patients with severe hepatic disease, severely impaired renal function or in generally reduced general condition also require special attention. Patients treated with class III anti-arrhythmic drug (e.g. Amiodarone) should be closely observed and ECG monitoring should be considered,
Like all local anesthetic drugs, bupivacaine can cause acute central nervous and cardiovascular toxic effects in cases of use leading to high concentrations in the blood.
There is increased risk of extensive or total spinal blockade in elderly patients and patients in late stages of pregnancy. The dose should there be reduced for these patients Spinal anesthesia can lead to a fall in blood pressure and bradycardia.

The risk can be reduced by means of intravenous administration of crystalloid or colloid solution. A fall in blood pressure should be treated immediately, for example with ephedrine 5- 10 mg intravenously, repeated as required.

Neurological disorders, such as multiple sclerosis, hemiplegia, paraplegia and neuromuscular disturbances are not thought to be adversely affected by spinal anaesthesia, but caution should be exercised.

Posology and method of administration:

B-cane heavy should only be used by clinicians with experience of regional anaesthesia or under their supervision. The lowest possible dose for adequate anesthesia should be used.

The doses given below are guides for adults and the dosage should be adjusted to the individual patient.
The dose should be reduced in elderly patients and patients in late stages of pregnancy.


Dose – ml

Dose – mg

Time to

onset of effect

in minutes


Duration of

effect in hours




1.5- 3ml

7.5-15 mg

5-8 min

2-3 hours

Surgery on

lower limbs,


hip surgery

2-4 ml

10-20 mg

5-8 min

2-3 hours






2-4 ml

10-20 mg

5-8 min

45-60 min

The recommended injection is in the L3 –L4 intervertebral space.

There is currently no experience of doses higher than 20 mg.


B-CANE Heavy is supplied in 4 ml OPC Glass Ampoule.